Phosphatidylcholine Transfer Protein Interacts with Thioesterase Superfamily Member 2 to Attenuate Insulin Signaling

Phosphatidylcholine transfer protein (PC-TP) is a phospholipid-binding protein that is enriched in liver and that interacts with thioesterase superfamily member 2 (THEM2). Mice lacking either protein exhibit improved hepatic glucose homeostasis and are resistant to diet-induced diabetes. Insulin rec...

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Hlavní autoři: Ersoy, Baran A., Tarun, Akansha, D’Aquino, Katharine, Hancer, Nancy J., Ukomadu, Chinweike, White, Morris F., Michel, Thomas, Manning, Brendan D., Cohen, David E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959124/
https://ncbi.nlm.nih.gov/pubmed/23901139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004111
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