Identification and characterization of trans-3-hydroxy-l-proline dehydratase and Δ(1)-pyrroline-2-carboxylate reductase involved in trans-3-hydroxy-l-proline metabolism of bacteria

trans-4-Hydroxy-l-proline (T4LHyp) and trans-3-hydroxy-l-proline (T3LHyp) occur mainly in collagen. A few bacteria can convert T4LHyp to α-ketoglutarate, and we previously revealed a hypothetical pathway consisting of four enzymes at the molecular level (J Biol Chem (2007) 282, 6685–6695; J Biol Che...

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Autores principales: Watanabe, Seiya, Tanimoto, Yoshiaki, Yamauchi, Seiji, Tozawa, Yuzuru, Sawayama, Shigeki, Watanabe, Yasuo
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958920/
https://ncbi.nlm.nih.gov/pubmed/24649405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.02.010
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