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Large-Scale Domain Motions and Pyridoxal-5′-Phosphate Assisted Radical Catalysis in Coenzyme B(12)-Dependent Aminomutases

Lysine 5,6-aminomutase (5,6-LAM) and ornithine 4,5-aminomutase (4,5-OAM) are two of the rare enzymes that use assistance of two vitamins as cofactors. These enzymes employ radical generating capability of coenzyme B(12) (5′-deoxyadenosylcobalamin, dAdoCbl) and ability of pyridoxal-5′-phosphate (PLP,...

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Bibliografiske detaljer
Main Authors: Maity, Amarendra Nath, Chen, Yung-Han, Ke, Shyue-Chu
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958899/
https://ncbi.nlm.nih.gov/pubmed/24562332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15023064
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