Cell-Based in Vitro Blood–Brain Barrier Model Can Rapidly Evaluate Nanoparticles’ Brain Permeability in Association with Particle Size and Surface Modification

The possibility of nanoparticle (NP) uptake to the human central nervous system is a major concern. Recent reports showed that in animal models, nanoparticles (NPs) passed through the blood–brain barrier (BBB). For the safe use of NPs, it is imperative to evaluate the permeability of NPs through the...

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Bibliographic Details
Main Authors: Hanada, Sanshiro, Fujioka, Kouki, Inoue, Yuriko, Kanaya, Fumihide, Manome, Yoshinobu, Yamamoto, Kenji
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958822/
https://ncbi.nlm.nih.gov/pubmed/24469316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15021812
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