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Cell-Based in Vitro Blood–Brain Barrier Model Can Rapidly Evaluate Nanoparticles’ Brain Permeability in Association with Particle Size and Surface Modification

The possibility of nanoparticle (NP) uptake to the human central nervous system is a major concern. Recent reports showed that in animal models, nanoparticles (NPs) passed through the blood–brain barrier (BBB). For the safe use of NPs, it is imperative to evaluate the permeability of NPs through the...

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Detalhes bibliográficos
Main Authors: Hanada, Sanshiro, Fujioka, Kouki, Inoue, Yuriko, Kanaya, Fumihide, Manome, Yoshinobu, Yamamoto, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958822/
https://ncbi.nlm.nih.gov/pubmed/24469316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15021812
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