Exploring T Cell Reactivity to Gliadin in Young Children with Newly Diagnosed Celiac Disease

Class II major histocompatibility molecules confer disease risk in Celiac disease (CD) by presenting gliadin peptides to CD4 T cells in the small intestine. Deamidation of gliadin peptides by tissue transglutaminase creates immunogenic peptides presented by HLA-DQ2 and DQ8 molecules to activate proi...

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Detalhes bibliográficos
Main Authors: Liu, Edwin, McDaniel, Kristen, Case, Stephanie, Yu, Liping, Gerhartz, Bernd, Ostermann, Nils, Fankhauser, Gabriela, Hungerford, Valerie, Zou, Chao, Luyten, Marcel, Seidl, Katherine J., Michels, Aaron W.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958769/
https://ncbi.nlm.nih.gov/pubmed/24724018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/927190
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