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A Model-Based Analysis of Culture-Dependent Phenotypes of mESCs

Mouse embryonic stem cells (mESCs) can be maintained in a proliferative and undifferentiated state over many passages (self-renewal) while retaining the potential to give rise to every cell type of the organism (pluripotency). Autocrine FGF4/Erk signalling has been identified as a major stimulus for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Herberg, Maria, Kalkan, Tüzer, Glauche, Ingmar, Smith, Austin, Roeder, Ingo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958526/
https://ncbi.nlm.nih.gov/pubmed/24643025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092496
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