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Gene Therapy for Neuropathic Pain by Silencing of TNF-α Expression with Lentiviral Vectors Targeting the Dorsal Root Ganglion in Mice

Neuropathic pain can be a debilitating condition. Many types of drugs that have been used to treat neuropathic pain have only limited efficacy. Recent studies indicate that pro-inflammatory mediators including tumor necrosis factor α (TNF-α) are involved in the pathogenesis of neuropathic pain. In t...

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Detalhes bibliográficos
Main Authors: Ogawa, Nobuhiro, Kawai, Hiromichi, Terashima, Tomoya, Kojima, Hideto, Oka, Kazuhiro, Chan, Lawrence, Maegawa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958473/
https://ncbi.nlm.nih.gov/pubmed/24642694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092073
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