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Continuous-Infusion Topotecan and Erlotinib: A Study in Topotecan-Pretreated Ovarian Cancer Assessing Shed Collagen Epitopes as a Marker of Invasiveness

BACKGROUND. Continuous-infusion topotecan with erlotinib has the potential to reverse topotecan resistance due to drug efflux mechanisms. We assessed the activity of such a regimen in ovarian cancer patients previously failing bolus topotecan. Assay for shed collagen epitopes recognized by antibody...

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Bibliografiske detaljer
Main Authors: Warner, Eiran, Liebes, Leonard, Levinson, Benjamin, Downey, Andrea, Tiersten, Amy, Muggia, Franco
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958467/
https://ncbi.nlm.nih.gov/pubmed/24563078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2013-0398
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