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Interaction of antimicrobial peptide Plantaricin149a and four analogs with lipid bilayers and bacterial membranes

The amidated analog of Plantaricin149, an antimicrobial peptide from Lactobacillus plantarum NRIC 149, directly interacts with negatively charged liposomes and bacterial membranes, leading to their lysis. In this study, four Pln149-analogs were synthesized with different hydrophobic groups at their...

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Detalhes bibliográficos
Main Authors: de Souza Lopes, José Luiz, Hissa, Denise Cavalcante, Melo, Vânia Maria Maciel, Beltramini, Leila Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Brazilian Society of Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958201/
https://ncbi.nlm.nih.gov/pubmed/24688525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1517-83822014005000007
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