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Adenoviral Delivery of Recombinant Hepatitis B Virus Expressing Foreign Antigenic Epitopes for Immunotherapy of Persistent Viral Infection

We previously reported a proof-of-concept study for curing chronic hepatitis B virus (HBV) infection using a foreign-antigen recombinant HBV (rHBV) as a gene therapy vector. Targeted elimination of wild-type HBV (wtHBV)-infected cells could be achieved by functionally activating an in situ T-cell re...

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Bibliografiske detaljer
Main Authors: Wang, Zhuo, Zhu, Kai, Bai, Weiya, Jia, Baosen, Hu, Hao, Zhou, Dongming, Zhang, Xiaoming, Zhang, Xinxin, Xie, Youhua, Bourgine, Maryline Mancini, Michel, Marie-Louise, Lan, Ke, Deng, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958094/
https://ncbi.nlm.nih.gov/pubmed/24371056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02756-13
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