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Morbillivirus Control of the Interferon Response: Relevance of STAT2 and mda5 but Not STAT1 for Canine Distemper Virus Virulence in Ferrets

The V proteins of paramyxoviruses control the innate immune response. In particular, the V protein of the genus Morbillivirus interferes with the signal transducer and activator of transcription 1 (STAT1), STAT2, and melanoma differentiation-associated protein 5 (mda5) signaling pathways. To charact...

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Detalhes bibliográficos
Main Authors: Svitek, Nicholas, Gerhauser, Ingo, Goncalves, Christophe, Grabski, Elena, Döring, Marius, Kalinke, Ulrich, Anderson, Danielle E., Cattaneo, Roberto, von Messling, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958063/
https://ncbi.nlm.nih.gov/pubmed/24371065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03076-13
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