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Downregulation of STRA6 in Adipocytes and Adipose Stromovascular Fraction in Obesity and Effects of Adipocyte-Specific STRA6 Knockdown In Vivo

To investigate the mechanisms by which elevated retinol-binding protein 4 (RBP4) causes insulin resistance, we studied the role of the high-affinity receptor for RBP4, STRA6 (stimulated by retinoic acid), in insulin resistance and obesity. In high-fat-diet-fed and ob/ob mice, STRA6 expression was de...

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Détails bibliographiques
Auteurs principaux: Zemany, Laura, Kraus, Bettina J., Norseen, Julie, Saito, Tsugumichi, Peroni, Odile D., Johnson, Randy L., Kahn, Barbara B.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958040/
https://ncbi.nlm.nih.gov/pubmed/24421389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01106-13
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