Abcb10 Role in Heme Biosynthesis In Vivo: Abcb10 Knockout in Mice Causes Anemia with Protoporphyrin IX and Iron Accumulation

Abcb10, member 10 of the ABC transporter family, is reportedly a part of a complex in the mitochondrial inner membrane with mitoferrin-1 (Slc25a37) and ferrochelatase (Fech) and is responsible for heme biosynthesis in utero. However, it is unclear whether loss of Abcb10 causes pathological changes i...

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Detalhes bibliográficos
Main Authors: Yamamoto, Masatatsu, Arimura, Hiroshi, Fukushige, Tomoko, Minami, Kentarou, Nishizawa, Yukihiko, Tanimoto, Akihide, Kanekura, Takuro, Nakagawa, Masayuki, Akiyama, Shin-ichi, Furukawa, Tatsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958026/
https://ncbi.nlm.nih.gov/pubmed/24421385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00865-13
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