Rosetting Plasmodium falciparum-Infected Erythrocytes Bind to Human Brain Microvascular Endothelial Cells In Vitro, Demonstrating a Dual Adhesion Phenotype Mediated by Distinct P. falciparum Erythrocyte Membrane Protein 1 Domains

Adhesion interactions between Plasmodium falciparum-infected erythrocytes (IE) and human cells underlie the pathology of severe malaria. IE cytoadhere to microvascular endothelium or form rosettes with uninfected erythrocytes to survive in vivo by sequestering IE in the microvasculature and avoiding...

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Detalhes bibliográficos
Main Authors: Adams, Yvonne, Kuhnrae, Pongsak, Higgins, Matthew K., Ghumra, Ashfaq, Rowe, J. Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958005/
https://ncbi.nlm.nih.gov/pubmed/24343658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01233-13
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