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Double Recombinant Mycobacterium bovis BCG Strain for Screening of Primary and Rationale-Based Antimycobacterial Compounds

Conventional antimycobacterial screening involves CFU analysis, which poses a great challenge due to slow growth of mycobacteria. Recombinant strains carrying reporter genes under the influence of constitutive promoters allow rapid and wide screening of compounds but without revealing their modes of...

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Detalhes bibliográficos
Main Authors: Singh, Vandana, Biswas, Rajesh Kumar, Singh, Bhupendra N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957833/
https://ncbi.nlm.nih.gov/pubmed/24342633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01301-13
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