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Loop-Mediated Isothermal Amplification for Rickettsia typhi (the Causal Agent of Murine Typhus): Problems with Diagnosis at the Limit of Detection

Murine typhus is a flea-borne disease of worldwide distribution caused by Rickettsia typhi. Although treatment with tetracycline antibiotics is effective, treatment is often misguided or delayed due to diagnostic difficulties. As the gold standard immunofluorescence assay is imperfect, we aimed to d...

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Autori principali: Dittrich, Sabine, Castonguay-Vanier, Josée, Moore, Catrin E., Thongyoo, Narongchai, Newton, Paul N., Paris, Daniel H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957756/
https://ncbi.nlm.nih.gov/pubmed/24371248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02786-13
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