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The Role of CRISPR-Cas Systems in Virulence of Pathogenic Bacteria

SUMMARY: Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) genes are present in many bacterial and archaeal genomes. Since the discovery of the typical CRISPR loci in the 1980s, well before their physiological role was revealed, their variable sequences h...

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Detalhes bibliográficos
Main Authors: Louwen, Rogier, Staals, Raymond H. J., Endtz, Hubert P., van Baarlen, Peter, van der Oost, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957734/
https://ncbi.nlm.nih.gov/pubmed/24600041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00039-13
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