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SCO5745, a Bifunctional RNase J Ortholog, Affects Antibiotic Production in Streptomyces coelicolor

The bacterial RNases J are considered bifunctional RNases possessing both endo- and exonucleolytic activities. We have isolated an RNase J ortholog from Streptomyces coelicolor encoded by the gene sco5745. We overexpressed a decahistidine-tagged version of SCO5745 and purified the overexpressed prot...

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Detalhes bibliográficos
Main Authors: Bralley, Patricia, Aseem, Madiha, Jones, George H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957725/
https://ncbi.nlm.nih.gov/pubmed/24415725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01422-13
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