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Mutations in Toll-Like Receptor 3 Are Associated with Elevated Levels of Rotavirus-Specific IgG Antibodies in IgA-Deficient but Not IgA-Sufficient Individuals

Double-stranded RNA (dsRNA) triggers immune-mediated responses through toll-like receptor 3 (TLR3), which is involved in innate antiviral defense. Low expression of TLR3 was recently suggested to contribute to susceptibility to rotavirus infection. Thus, we investigated the role of two TLR3 polymorp...

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Bibliographische Detailangaben
Hauptverfasser: Günaydın, Gökçe, Nordgren, Johan, Svensson, Lennart, Hammarström, Lennart
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957673/
https://ncbi.nlm.nih.gov/pubmed/24371259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00666-13
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