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A Genomewide Overexpression Screen Identifies Genes Involved in the Phosphatidylinositol 3-Kinase Pathway in the Human Protozoan Parasite Entamoeba histolytica

Entamoeba histolytica is a protozoan parasite that causes amoebic dysentery and liver abscess. E. histolytica relies on motility, phagocytosis, host cell adhesion, and proteolysis of extracellular matrix for virulence. In eukaryotic cells, these processes are mediated in part by phosphatidylinositol...

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Bibliographische Detailangaben
Hauptverfasser: Koushik, Amrita B., Welter, Brenda H., Rock, Michelle L., Temesvari, Lesly A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957588/
https://ncbi.nlm.nih.gov/pubmed/24442890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00329-13
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