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Three-dimensional Organization of pKi-67: A Comparative Fluorescence and Electron Tomography Study Using Fluoronanogold

The monoclonal antibody (MAb) Ki-67 is routinely used in clinical studies to estimate the growth fraction of tumors. However, the role of pKi-67, the protein detected by the Ki-67 MAb, remains elusive, although some biochemical data strongly suggest that it might organize chromatin. To better unders...

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Autors principals: Cheutin, Thierry, O'Donohue, Marie-Françoise, Beorchia, Adrien, Klein, Christophe, Kaplan, Hervé, Ploton, Dominique
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957551/
https://ncbi.nlm.nih.gov/pubmed/14566014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/002215540305101102
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