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An unappreciated role for RNA surveillance

BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA surveillance mechanism that detects and degrades mRNAs with premature termination codons (PTC(+ )mRNAs). In mammals, a termination codon is recognized as premature if it lies more than about 50 nucleotides upstream of the final intr...

詳細記述

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書誌詳細
主要な著者: Hillman, R Tyler, Green, Richard E, Brenner, Steven E
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC395752/
https://ncbi.nlm.nih.gov/pubmed/14759258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-2-r8
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