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Distinct functional and pharmacological properties of triheteromeric GluN1/GluN2A/GluN2B NMDA receptors

NMDA receptors are tetrameric ligand-gated ion channels comprised of GluN1, GluN2, and GluN3 subunits. Two different GluN2 subunits have been identified in most NMDA receptor-expressing cells, and the majority of native receptors are triheteromers containing two GluN1 and two different GluN2. In con...

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Detalhes bibliográficos
Main Authors: Hansen, Kasper B., Ogden, Kevin K., Yuan, Hongjie, Traynelis, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957490/
https://ncbi.nlm.nih.gov/pubmed/24607230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.01.035
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