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Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin

SIRT2 is a member of the mammalian sirtuin family (SIRT1–7). As compared with other sirtuins, SIRT2 is found primarily in the cytoplasm. It regulates multiple physiological processes. However, the precise role of SIRT2 in skin cancer remains unclear. Here, we show that SIRT2 is down-regulated in hum...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ming, Mei, Qiang, Lei, Zhao, Baozhong, He, Yu-Ying
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957270/
https://ncbi.nlm.nih.gov/pubmed/24438005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.12323
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