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Role of Tet1 in genomic imprinting erasure
Genomic imprinting is an allele-specific gene expression system important for mammalian development and function (1). The molecular basis of genomic imprinting is allele-specific DNA methylation (1,2). While it is well known that the de novo DNA methyltransferases Dnmt3a/b are responsible for the es...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3957231/ https://ncbi.nlm.nih.gov/pubmed/24291790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12805 |
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