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Linaclotide: Promising IBS-C Efficacy in an Era of Provisional Study Endpoints
Recent disappointing developments in the pharmacotherapy of irritable bowel syndrome (IBS) have not dampened the enthusiasm surrounding linaclotide, a novel guanylate cyclase-C agonist for the management of constipation-predominant IBS (IBS-C). Two recent phase 3 studies reporting on a single, daily...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3957218/ https://ncbi.nlm.nih.gov/pubmed/23160292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2012.325 |
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