Nogo-A-deficient Transgenic Rats Show Deficits in Higher Cognitive Functions, Decreased Anxiety, and Altered Circadian Activity Patterns

Decreased levels of Nogo-A-dependent signaling have been shown to affect behavior and cognitive functions. In Nogo-A knockout and knockdown laboratory rodents, behavioral alterations were observed, possibly corresponding with human neuropsychiatric diseases of neurodevelopmental origin, particularly...

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Detalhes bibliográficos
Main Authors: Petrasek, Tomas, Prokopova, Iva, Sladek, Martin, Weissova, Kamila, Vojtechova, Iveta, Bahnik, Stepan, Zemanova, Anna, Schönig, Kai, Berger, Stefan, Tews, Björn, Bartsch, Dusan, Schwab, Martin E., Sumova, Alena, Stuchlik, Ales
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957197/
https://ncbi.nlm.nih.gov/pubmed/24672453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2014.00090
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