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Association of p53 genomic instability with the glutathione S-transferase null genotype in gastric cancer in the Portuguese population.

AIMS: p53 gene mutations are the most common genetic changes known to occur in human cancer. In previous studies, the presence of alterations to the p53 gene has been linked to the null phenotype of the glutathione S-transferase mu gene (GSTM1). GSTM1 appears to be part of a protective mechanism aga...

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Библиографические подробности
Главные авторы: Conde, A R, Martins, G, Saraiva, C, Rueff, J, Monteiro, C
Формат: Artigo
Язык:Inglês
Опубликовано: 1999
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC395686/
https://ncbi.nlm.nih.gov/pubmed/10621833
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