Cerebrospinal Fluid Biomarker and Brain Biopsy Findings in Idiopathic Normal Pressure Hydrocephalus

BACKGROUND: The significance of amyloid precursor protein (APP) and neuroinflammation in idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD) is unknown. OBJECTIVE: To investigate the role of soluble APP (sAPP) and amyloid beta (Aβ) isoforms, proinflammatory cytokines, a...

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Détails bibliographiques
Auteurs principaux: Pyykkö, Okko T., Lumela, Miikka, Rummukainen, Jaana, Nerg, Ossi, Seppälä, Toni T., Herukka, Sanna-Kaisa, Koivisto, Anne M., Alafuzoff, Irina, Puli, Lakshman, Savolainen, Sakari, Soininen, Hilkka, Jääskeläinen, Juha E., Hiltunen, Mikko, Zetterberg, Henrik, Leinonen, Ville
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956805/
https://ncbi.nlm.nih.gov/pubmed/24638077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091974
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