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Protective action of Citrullus colocynthis seed extracts against the deleterious effect of streptozotocin on both in vitro glucose-stimulated insulin release from rat pancreatic islets and in vivo glucose homeostasis

Citrullus colocynthis extracts improve glucose homeostasis in alloxan- or streptozotocin (STZ)-induced diabetic rats. Little is known, however, regarding the protective effect of these extracts against the β-cytotoxic action of STZ. In the present study, an H(2)O-methanol extract was found to suppre...

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Detalhes bibliográficos
Main Authors: BENARIBA, NABILA, BELLAKDHAR, WAFAA, DJAZIRI, RABEH, HUPKENS, EMELINE, LOUCHAMI, KARIM, MALAISSE, WILLY J.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956620/
https://ncbi.nlm.nih.gov/pubmed/24648906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2012.5
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