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Lapatinib inhibits stem/progenitor proliferation in preclinical in vitro models of ductal carcinoma in situ (DCIS)

Breast-conserving surgery for ductal carcinoma in situ (DCIS) is often combined with irradiation, reducing recurrence rates to 20% within 10 years; however, there is no change in overall survival. Evidence in the invasive breast indicates that breast cancer stem cells (CSCs) are radiotherapy-resista...

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Detalhes bibliográficos
Main Authors: Farnie, Gillian, Johnson, Rachael L, Williams, Kathryn E, Clarke, Robert B, Bundred, Nigel J
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956537/
https://ncbi.nlm.nih.gov/pubmed/24247151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27201
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