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Pathway Analysis for Drug Repositioning Based on Public Database Mining

[Image: see text] Sixteen FDA-approved drugs were investigated to elucidate their mechanisms of action (MOAs) and clinical functions by pathway analysis based on retrieved drug targets interacting with or affected by the investigated drugs. Protein and gene targets and associated pathways were obtai...

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Detalhes bibliográficos
Main Authors: Pan, Yongmei, Cheng, Tiejun, Wang, Yanli, Bryant, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956470/
https://ncbi.nlm.nih.gov/pubmed/24460210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci4005354
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