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BRCA1 and BRCA2 proteins: roles in health and disease.

Between 5% and 10% of all breast cancer is hereditary, with patients having a strong family history of the disease. The remaining 90-95% of cases are classed as sporadic. Within the inherited group, 80-90% of cases are the result of germline mutations affecting two recently identified genes: BRCA1 a...

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Detalhes bibliográficos
Main Authors: Duncan, J A, Reeves, J R, Cooke, T G
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395646/
https://ncbi.nlm.nih.gov/pubmed/10193517
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