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Combinatorial Immunotherapy of Polyinosinic-Polycytidylic Acid and Blockade of Programmed Death-1 Induces Effective CD8 T Cell Responses against Established Tumors

PURPOSE: Epitope-based cancer vaccines capable of inducing CD8 T cell responses to tumor-associated antigens (TAAs) expressed by tumor cells have been considered as attractive alternatives for the treatment of some types of cancer. However, reliable TAAs have not been identified for most malignant d...

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Detalhes bibliográficos
Main Authors: Nagato, Toshihiro, Lee, Young-Ran, Harabuchi, Yasuaki, Celis, Esteban
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956448/
https://ncbi.nlm.nih.gov/pubmed/24389326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2781
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