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Sodium valproate exposure during the brain growth spurt transiently impairs spatial learning in prepubertal rats

The brain is extremely vulnerable to teratogenic insults during the brain growth spurt, a period that starts during the third trimester of human gestation and is characterized by synaptogenesis establishment of neuronal circuits. While the treatment of epilepsy during pregnancy increases the risk of...

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Autors principals: Filgueiras, Cláudio C., Pohl-Guimarães, Fernanda, Krahe, Thomas E., Medina, Alexandre E.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956441/
https://ncbi.nlm.nih.gov/pubmed/23178315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2012.11.007
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