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Metallothionein-II Inhibits Lipid Peroxidation and Improves Functional Recovery after Transient Brain Ischemia and Reperfusion in Rats

After transient cerebral ischemia and reperfusion (I/R), damaging mechanisms, such as excitotoxicity and oxidative stress, lead to irreversible neurological deficits. The induction of metallothionein-II (MT-II) protein is an endogenous mechanism after I/R. Our aim was to evaluate the neuroprotective...

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Detalhes bibliográficos
Main Authors: Diaz-Ruiz, Araceli, Vacio-Adame, Patricia, Monroy-Noyola, Antonio, Méndez-Armenta, Marisela, Ortiz-Plata, Alma, Montes, Sergio, Rios, Camilo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956286/
https://ncbi.nlm.nih.gov/pubmed/24719677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/436429
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