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Antitumoral effect of PLK-1-inhibitor BI2536 in combination with cisplatin and docetaxel in squamous cell carcinoma cell lines of the head and neck

Inhibition of the polo-like-kinase-1 (PLK-1) has been shown to be effective in several haematological and solid tumor models. In this systemic in vitro study, the antitumor effect of BI2536, a small molecule inhibitor of PLK-1, in combination with cisplatin and docetaxel was examined in nine squamou...

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Dettagli Bibliografici
Autori principali: WAGENBLAST, JENS, HIRTH, DANIEL, ECKARDT, ANNE, LEINUNG, MARTIN, DIENSTHUBER, MARC, STÖVER, TIMO, HAMBEK, MARKUS
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956268/
https://ncbi.nlm.nih.gov/pubmed/24649162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2012.45
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