Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells

Di- and trimethylation of lysine 27 on histone H3 (H3K27me2/3) is an important gene repression mechanism. H3K27me2/3-specific demethylase, Jmjd3, was expressed in the inner nuclear layer during late retinal development. In contrast, H3K27 methyltransferase, Ezh2, was highly expressed in the embryoni...

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Detalles Bibliográficos
Main Authors: Iida, Atsumi, Iwagawa, Toshiro, Kuribayashi, Hiroshi, Satoh, Shinya, Mochizuki, Yujin, Baba, Yukihiro, Nakauchi, Hiromitsu, Furukawa, Takahisa, Koseki, Haruhiko, Murakami, Akira, Watanabe, Sumiko
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956141/
https://ncbi.nlm.nih.gov/pubmed/24572572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311480111
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