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Methoxychlor-Induced Ovarian Follicle Toxicity in Mice: Dose and Exposure Duration-Dependent Effects

BACKGROUND: Methoxychlor (MXC) is specifically known to target ovarian antral follicles, increasing atresia (death via apoptosis) in them. This is of concern because females are born with a finite pool of ovarian follicles. Only limited studies have explored the phenomenon of a reduced fertility thr...

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Detalhes bibliográficos
Main Authors: Paulose, Tessie, Tannenbaum, Lawrence V., Borgeest, Christina, Flaws, Jodi A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956042/
https://ncbi.nlm.nih.gov/pubmed/22495784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrb.21007
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