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An infectious viroid RNA replicon evolved from an in vitro-generated non-infectious viroid deletion mutant via a complementary deletion in vivo.
The 359 nucleotides (nt) long potato spindle tuber prototype viroid (PSTVd) is sensitive to experimentally introduced mutations as the substitution or deletion of a single nucleotide usually abolishes its infectivity, although certain sequence alterations are tolerated. This is illustrated by the fa...
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Autori principali: | , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
1994
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395597/ https://ncbi.nlm.nih.gov/pubmed/7813454 |
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