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An infectious viroid RNA replicon evolved from an in vitro-generated non-infectious viroid deletion mutant via a complementary deletion in vivo.

The 359 nucleotides (nt) long potato spindle tuber prototype viroid (PSTVd) is sensitive to experimentally introduced mutations as the substitution or deletion of a single nucleotide usually abolishes its infectivity, although certain sequence alterations are tolerated. This is illustrated by the fa...

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Bibliografiska uppgifter
Huvudupphovsmän: Wassenegger, M, Heimes, S, Sänger, H L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC395597/
https://ncbi.nlm.nih.gov/pubmed/7813454
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