The adenovirus E1A protein overrides the requirement for cellular ras in initiating DNA synthesis.

The adenovirus E1A protein can induce cellular DNA synthesis in growth-arrested cells by interacting with the cellular protein p300 or pRb. In addition, serum- and growth factor-dependent cells require ras activity to initiate DNA synthesis and recently we have shown that Balb/c 3T3 cells can be blo...

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Publicat a:EMBO J
Autors principals: Stacey, D W, Dobrowolski, S F, Piotrkowski, A, Harter, M L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395590/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7813447/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06957.x
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