A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90.

Wee1 protein kinase regulates the length of G2 phase by carrying out the inhibitory tyrosyl phosphorylation of Cdc2-cyclin B kinase. Mutations were isolated that suppressed the G2 cell cycle arrest caused by overproduction of Wee1. One class of swo (suppressor of wee1 overproduction) mutation, exemp...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Aligue, R, Akhavan-Niak, H, Russell, P
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7813446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06956.x
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