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Regulatory T Cells Limit Induction of Protective Immunity and Promote Immune Pathology Following Intestinal Helminth Infection

Foxp3(+) regulatory T cells (T(regs)) have a well-characterized role in limiting autoimmunity and dampening deleterious immune responses. However, a potential consequence of the immunosuppressive function of T(regs) can be the limitation of protective immunity to infectious pathogens. Parasitic infe...

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Detalhes bibliográficos
Main Authors: Sawant, Deepali V., Gravano, David M., Vogel, Peter, Giacomin, Paul, Artis, David, Vignali, Dario A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955731/
https://ncbi.nlm.nih.gov/pubmed/24532574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202502
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