Nuclear Nox4-Derived Reactive Oxygen Species in Myelodysplastic Syndromes

A role for intracellular ROS production has been recently implicated in the pathogenesis and progression of a wide variety of neoplasias. ROS sources, such as NAD(P)H oxidase (Nox) complexes, are frequently activated in AML (acute myeloid leukemia) blasts and strongly contribute to their proliferati...

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Detalhes bibliográficos
Main Authors: Guida, Marianna, Maraldi, Tullia, Beretti, Francesca, Follo, Matilde Y., Manzoli, Lucia, De Pol, Anto
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955662/
https://ncbi.nlm.nih.gov/pubmed/24719867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/456937
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