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Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans

Prior to the advent of synthetic nematocides, natural products such as seaweed were used to control nematode infestations. The nematocidal agent in seaweed is betaine, an amino acid that functions as an osmolyte and methyl donor. However, the molecular mechanisms of betaine toxicity are unknown. Her...

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Autores principales: Peden, Aude S., Mac, Patrick, Fei, You-Jun, Castro, Cecilia, Jiang, Guoliang, Murfitt, Kenneth J., Miska, Eric A., Griffin, Julian L., Ganapathy, Vadivel, Jorgensen, Erik M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955162/
https://ncbi.nlm.nih.gov/pubmed/24212673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3575
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