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Obesity is associated with higher 4E-BP1 expression in endometrial cancer

PURPOSE: Obesity is associated with risk and prognosis of endometrial cancer (EC), and the mammalian target of rapamycin complex 1 (mTORC1) pathway may play an instrumental role. We sought to explore the associations between cellular proliferation, Akt, and 4E binding protein-1 (4E-BP1) (a downstrea...

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Detalhes bibliográficos
Main Authors: Libby, Emily Falk, Azrad, Maria, Novak, Lea, Vazquez, Ana I, Wilson, Tamara R, Demark-Wahnefried, Wendy
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955094/
https://ncbi.nlm.nih.gov/pubmed/24639918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CBF.S53530
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