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Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins.
hnRNP A1 is a pre-mRNA binding protein that antagonizes the alternative splicing activity of splicing factors SF2/ASF or SC35, causing activation of distal 5' splice sites. The structural requirements for hnRNP A1 function were determined by mutagenesis of recombinant human hnRNP A1. Two conser...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
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1994
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395506/ https://ncbi.nlm.nih.gov/pubmed/7957114 |
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