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A Single Viral Gene Determines Lethal Cross-Species Neurovirulence of Baboon Herpesvirus HVP2

Alpha-herpesviruses can produce more severe infections in non-natural host species than in their natural host. Isolates of the baboon alpha-herpesvirus Papiine herpesvirus 2 (HVP2) are either very neurovirulent in mice (subtype nv) or non-virulent (subtype ap), but no such difference is evident in t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Black, Darla, Ohsawa, Kazutaka, Tyler, Shaun, Maxwell, Lara, Eberle, R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955001/
https://ncbi.nlm.nih.gov/pubmed/24606686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.12.038
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