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Fibroblasts from long-lived species of mammals and birds show delayed, but prolonged, phosphorylation of ERK

Fibroblasts from long-lived mutant mice show diminished phosphorylation of the stress-activated protein kinases ERK1/2 after exposure to peroxide, cadmium, or paraquat. We have now evaluated the kinetics of ERK phosphorylation in fibroblasts from long-lived and short-lived species of mammals and bir...

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書目詳細資料
Main Authors: Elbourkadi, Najoua, Austad, Steven N, Miller, Richard A
格式: Artigo
語言:Inglês
出版: BlackWell Publishing Ltd 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954945/
https://ncbi.nlm.nih.gov/pubmed/24219321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12172
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